Oligonucleotide & Aptamer Conjugation Services
Oligonucleotide conjugates are versatile tools used across research, diagnostics, and therapeutics.
Oligonucleotide conjugates improve the sensitivity and specificity of molecular diagnostics, such as PCR assays and microarrays, facilitating the detection of pathogens, cancer biomarkers, and genetic variations.
In therapeutics, oligonucleotide conjugates offer targeted treatments by modulating gene expression, to help manage genetic disorders, cancers, and viral infections. Conjugations with lipids or peptides enhance stability and targeted delivery, improving efficacy and reducing side effects.
Oligonucleotide & Aptamer Conjugates
Drawing on our experience in 5', 3', and internal chain modifications, our solutions are precisely engineered to meet your specific needs.
Previous Projects
Antibody Oligonucleotides for Customers IP
This project centred on the development of antibody oligonucleotide conjugates, coupled with the innovation of novel purification technologies. These advancements were designed to enhance the efficacy and purity of the conjugates by efficiently removing all unconjugated materials. This dual approach not only improved the specific binding capabilities of the conjugates but also ensured higher purity and functionality in subsequent applications.
Nanobody with Oligonucleotide & Fluorescent Dye
This project involved developing nanobodies with single oligonucleotides attached, with the aim of enhancing targeted molecular interactions. Additionally, control materials were prepared, featuring nanobodies with single oligonucleotides and fluorescent dyes. These controls serve as positive references within their protocol, facilitating the verification and calibration of assay performance, and ensuring reliability and accuracy in experimental outcomes.
Single Strand DNA attached to Magnetic Particle
This project focused on the attachment of single strands of DNA to microparticles, and was specifically engineered to allow for unimpeded interaction with DNA polymerase enzymes. This innovative design ensures that the polymerase can effectively interact with the DNA strands for enzymatic processes, such as replication and transcription, without the physical hindrance typically associated with surface attachment.